Mesothelioma Survival Rates & Statistics by Age, Gender & Race

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What Are Mesothelioma Survival Rates?

When discussing mesothelioma survival rates, you may hear other relate terms such as life anticipation, which is the average time a person is expected to live based on birth year, current age, gender and other factors .
Mesothelioma affects life anticipation because the cancer reduces the number of years a patient is expected to live .
A 2015 meta study published in Translational Oncology analyzed 20 years of data, collected from 1992 to 2012. The five-year survival rate for peritoneal mesothelioma patients was more than five times higher than the rate for pleural patients .
Pleural and Peritoneal Mesothelioma Survival Rates

Year(s) Pleural Peritoneal
1 year 73% 92%
3 years 23% 74%
5 years 12% 52%
10 years 4.7% 39%

Source:
“Changing Pattern in Malignant Mesothelioma Survival,” Translational Oncology, 2015.

5-Year Relative Survival Rates for Mesothelioma

proportional survival rates are a way of comparing the survival of people with a specific disease over a period of prison term to those who don ’ t have the disease. The clock period is typically five years after diagnosis .
The rate is calculated by dividing the percentage of patients inactive alive at the end of the prison term period by the share of people in the general population who are hush alive. The resulting rate reveals if the disease shortens life span .
The National Cancer Institute ’ randomness Surveillance, Epidemiology, and end Results platform, besides known as SEER, groups cancer survival rates into localized, regional and aloof stages. This basically distills the four pleural mesothelioma stages into three, with place representing stage 1, regional approximately representing stages 2 and 3, and aloof representing phase 4 .

Factors Affecting Mesothelioma Survival Rates

There are respective factors that affect how long a person will live after a mesothelioma diagnosis, these include a person ’ s general health, tumor location and the mesothelioma cell type .

Individual Characteristics and Mesothelioma Survival

  • Tumor Location
  • Stage of disease
  • Mesothelioma cell type
  • Age at diagnosis and overall health
  • Gender
  • Race/Ethnicity

A 2018 analysis of 888 cases in the National Mesothelioma Virtual Bank age group identified median overall survival of 15 months, on average, for pleural and peritoneal patients combined .
The most authoritative factors associated with better survival were old age ( less then 45 ), female gender, epithelioid cell type, stage 1 disease, peritoneal happening and treatment combining operation with chemotherapy .

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Mesothelioma Tumor Location

There are four types of mesothelioma, and the locate where the cancer originates affects patient outcomes. Survival is importantly better for peritoneal patients .
immediate fact :
half of peritoneal patients who undergo HIPEC live longer than five years .
An advance peritoneal mesothelioma therapy called hyperthermic intraperitoneal chemotherapy ( HIPEC ) has importantly improved survival rates for this cancer .
The operation combines cytoreductive operating room and heated chemotherapy. not everyone qualifies for this aggressive procedure, but more than one-half who do live at least five years .
This compares to a median survival of less than 12 months for patients with pleural tumors. In choose studies, heated chemotherapy has boosted peritoneal survival to between 40 and 92 months .
A 2020 analyze conducted at Brigham and Women ’ s Hosptial tested the equivalent operation and heated chemotherapy on pleural mesothelioma patients. It reported acute kidney injury in 48.3 % of patients, and none of these patients experienced a survival benefit from the procedure. What works for one type of mesothelioma may not work for another type .
The remaining two types of this asbestos-related cancer are pericardial and testicular. in concert, these report for less than 2 % of all cases. median survival for testicular mesothelioma, the rarest type, is 24 months .
pericardial mesothelioma is very rare, with only 200 document cases in the checkup literature. It develops on the lining of the heart and has a medial survival ranging from six weeks to 15 months .

Stage of Disease

The stage of mesothelioma at diagnosis is a firm predictor of overall survival. People with stage 1 or stage 2 mesothelioma, before cancer has spread, have the best survival rates .
Early-stage patients who receive prompt treatment feel improved survival. They are more likely to qualify for operating room and other aggressive treatments. More aggressive therapies are associated with better outcomes .

Video of Dr. Farid Gharagozloo, Robotic thoracic surgeon, explaining why an early mesothelioma diagnosis is critical.

Watch: Robotic pectoral surgeon Dr. Farid Gharagozloo explains why early diagnosis is so important for mesothelioma patients .
Most cases of pleural mesothelioma are not diagnosed until stage 3 or stage 4 .
At these stages, the tumor is large or has spread beyond the master cancer placement. Being diagnosed at subsequently stages mean the disease is more difficult to treat and is associated with poorer survival rates .
There is no establish cancer staging arrangement for peritoneal mesothelioma. Some researchers have developed their own systems based on the TNM scaffolding system. In TNM, T = tumor size, N = lymph node involvement and M = metastasis ( cancer spread ) to describe the extent of cancer .
One case is the peritoneal cancer index ( PCI ), which places this tumor type into three stages alternatively of the usual four for other cancers. A 2011 international study involving 294 patients treated with cytoreductive operating room and HIPEC, used PCI to describe affected role survival .
Peritoneal Mesothelioma Survival by Peritoneal Cancer Index (PCI) Staging

PCI Stage Year 1 Year 5
Stage 1 95% 87%
Stage 2 87% 53%
Stage 3 66% 29%

Source: “ A novel tumor-node-metastasis ( TNM ) staging system of circulate malignant peritoneal mesothelioma using consequence analysis of a multi-institutional database*, ” Cancer, 2011 .
pleural mesothelioma does not have favorable survival rates when compared with the survival rates of peritoneal disease. The pleural disease can be harder to treat .
Patients much are not diagnosed early adequate to receive the most aggressive available cancer therapies and may not be healthy enough to withstand invasive surgeries in particular .
Pleural Mesothelioma Median Survival by Stage

Stage 1 Stage 2 Stage 3 Stage 4
22.2 months 20 months 17.9 months 14.9 months

Source: “ The IASLC mesothelioma staging project, ” Journal of Thoracic Oncology, 2016 .

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Mesothelioma Cell Type (Tumor Histology)

The mesothelioma cell character, or tumor histology, impacts patient survival. The cancer has three chief cell types : Epithelioid, sarcomatoid and biphasic .
The most common cell character is epithelioid, which is besides the least aggressive. It responds best to treatment. median survival for patients with this cell character is 12 to 24 months .
Sarcomatoid mesothelioma is the most aggressive cell type. Patients with this diagnosis have a median survival of six to eight months .
Biphasic tumors have epithelioid and sarcomatoid features. More epithelial cells mean a better prognosis for mesothelioma patients. If the tumor is by and large sarcomatoid cells, life anticipation is decreased. Patients with a biphasic cell diagnosis have a median survival of around 13 months .

Age at Diagnosis and Overall Health

Older mesothelioma patients have lower survival rates, on average, compared with younger patients. More than 55 % of patients diagnosed before the senesce of 50 exist one year. Less than 30 % of patients 75 or older live the same total of time .
One-Year Mesothelioma Survival by Age

Age Range 1-Year Survival Rate
< 50 57.2%
50 – 64 51.2%
65 – 74 40.9%
75+ 28.5%

Patients diagnosed before age 50 have an estimated 25 % chance of surviving a ten. That drops to 5.4 % for patients between the ages of 50 and 64 .
The five-year survival rate for mesothelioma patients diagnosed between ages 65-74 is 6.7 %. That rate falls to 3.8 % for people 75 and older at diagnosis .
Younger patients tend to be healthier than older patients, which means they are eligible for more aggressive and effective therapies .
Younger patients besides are less likely to suffer from other chronic conditions such as pneumonic disease, diabetes or a history of other cancers. Better general health allows for registration in clinical trials, excessively .
Mesothelioma survival rate by age and gender table

Gender

Most asbestos exposures occur in the workplace. Industrial jobs traditionally held by men present the highest risk. This helps explain why men account for the majority of all cases .
however, even though men make up most cases of the disease, women with mesothelioma appear to survive longer than men careless of long time, cancer stage, raceway or type of treatment .
For every senesce group studied in the SEER program, women fared importantly better than men .
Mesothelioma Survival Rates by Gender

Gender 1 Year 2 Years 3 Years 4 Years 5 Years
Males 37.6% 17.4% 10.4% 7.7% 5.9%
Females 45.4% 29.3% 22.2% 18.6% 16.0%

There are respective possible reasons why women fare better than men. Some researchers believe the better survival could be explained by hormonal differences between sexes .
Women are more likely to be diagnosed with peritoneal mesothelioma, excessively. This tumor character has better survival compared with pleural tumors, which are more coarse among men. This skews the survival rates to favor women living longer, on average .
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Race/Ethnicity

Mesothelioma is about exclusive to white individuals, who make up 95 % of patients .
separate of this dispute is because black and hispanic individuals are less likely to be diagnosed with any character of cancer, including mesothelioma .
besides, colored individuals historically may have been less probably to hold industrial jobs associated with big asbestos exposure. Data from SEER shows blacks and Hispanics account for only 8 % of all cancer diagnoses .
Mesothelioma Survival Rates by Race

Race 1 Year 2 Years 3 Years 4 Years 5 Years
White* 39.7% 20.2% 12.9% 9.8% 7.8%
Black and Hispanic 35.2% 21.4% 16% 14.3% 12%

A 2015 report of 13,734 pleural mesothelioma cases in the SEER database found black patients lived longer than white patients despite being less probable to undergo aggressive operating room .
typically, patients who have surgery survive longer than those who do not .

How Do Mesothelioma Survival Rates Apply to Me?

Depending on the path of discussion you choose and your individual circumstances, you may live longer than the general mesothelioma survival rates suggest. Cancer survival rates don ’ t take holocene advances in treatment, such as immunotherapy and other target therapies available through clinical trials, into account .
survival rates entirely considers people diagnosed in the past. Anyone diagnosed today may have more available discussion options and a better prognosis going ahead .
Thanks to advances in mesothelioma treatments, many patients are beating the odds and living beyond modal survival rates .

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“ I belong to a group of cancer patients who live with a gloomy prognosis. I know I have no cure — yet — but am encouraged with every new study, mesothelioma treatment approval and inspiring survivor story. ” Emily Ward
pleural Mesothelioma Survivor

Ways to Improve Mesothelioma Survival Rates

many long-run mesothelioma survivors attribute their success live with the disease to a multidisciplinary approach to treatment. many in this group include the pursuit factors as helping them do well after diagnosis .

  • Seeking care and treatment from mesothelioma specialists
  • Trying clinical trials
  • Seeking referrals for exercise and rehabilitation to rebuild strength
  • Making nutritional changes to improve health and well-being
  • Trying complementary and alternative therapies in conjunction with, but not in place of, conventional cancer treatment

Common Questions About Mesothelioma Survival Rates

Is mesothelioma always fateful ?
malignant mesothelioma is considered an aggressive and black disease. Most mesothelioma patients only survive approximately 12 months after diagnosis. There is no cure for this cancer, but with discussion, patients have extended their life expectancies well beyond their initial prognosis .
What is the difference between a mesothelioma survival rate and mortality pace ?

survival rates refer to the percentage of cancer patients who live a certain number of years after their diagnosis. For exemplar, 23 % of pleural mesothelioma patients live for three years or more. The mesothelioma deathrate rate is the number of deaths within specific geographic locations and groups of people. For case, in 2015, there were 2,597 mesothelioma deaths in the United States .
How does the survival rate of mesothelioma compare to lung cancer ?
The five-year survival rate for mesothelioma patients is approximately 12 %. relatively, about 18 % of asbestos-related lung cancer patients survive more than five years after diagnosis .
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